THE CLINICAL CASE OF HEMIFACIAL MICROSOMIA IN THE NEWBORN BOY FROM MOTHER WITH Z-21

Hemifacial Microsomia (HFM) is a term used to identify facial deformities associated with the development ofthe first and second pairs of branchial arches, characterized by underdevelopment one half face. One typeof hemifacial microsomia oculo-auriculo-vertebral dysplasia or Goldenhar syndrome.The incidence HFM 1:3500-1:7000 live births occurs in 1 case per 1000 children congenitaldeafness. The ratio boys girls 3:2. etiology type inheritance studied insufficiently. There are threepossible pathogenetic models: vascular abnormalities hemorrhages craniofacial region, damage Meckel'scartilage, abnormal cell cranial nerve crest. Environmental factors, maternal internal factors,and genetic factors (OTX2, PLCD3, MYT1 mutations) may also cause microsomia.The article demonstrates clinical newborn boy from mother Z-21 inthe form deformation left auricle atresia auditory canal "false" ears on right, combinedwith congenital anomaly heart (atrial septal defect) brain (hypoplasia corpus callosum).Emphasis placed need involving multidisciplinary team specialists management thispatient both neonatal period system subsequent follow-up.